T cell immunity to cytomegalovirus studied in HIV patients after HAART.

2004 NOV 29 - (NewsRx.com & NewsRx.net) -- Researchers have assessed human cytomegalovirus-specific T cell immunity in HIV-infected patients in different disease stages following HAART and in long-term non-progressors.

"T cell immunity to human cytomegalovirus (HCMV) was assessed in HAART-treated HIV-1 infected patients (9 asymptomatic, CDC group A; and 22 symptomatic, CDC group B), and in eight HIV-1 long term non-progressors. Patients were either prospectively or cross-sectionally examined for CD4+ T cell counts, HIV RNA load, HCMV leukoDNAemia, HCMV DNA in urine, lymphoproliferative response (LPR) to HCMV and phytohemagglutinin (PHA), and cytokine secretion …